Cathedral
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Evidence, people, agents, and tools in one research record.

Cathedral
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Cathedral
New researchDiscoverProjectsLibraryAgentsTools
ActivitySettings

Evidence, people, agents, and tools in one research record.

Cathedral

Problem decomposition

Why chain: Artemisinin Resistance

Seeded from the Artemisinin Resistance concept page using the STANDARD explanation layer.

Problem statement

Why does Artemisinin Resistance work the way Cathedral currently explains it? Build a recursive why-chain that separates mechanisms, evidence, unresolved assumptions, and concrete research tasks.

active
Progress0%

Claim flow

What has to become true.

4 claims

Claim 1

root

Define the phenomenon

Claim 2

1 deps

Separate assumptions from evidence

Claim 3

1 deps

Find the bottleneck

Claim 4

1 deps

Test the strongest rival explanation

Tier 1open

Collect observations for Why chain: Artemisinin Resistance

Gather small, timestamped observations using a shared template. Prioritize clean metadata over interpretation.

Current knowledge

Why does Artemisinin Resistance work the way Cathedral currently explains it? Build a recursive why-chain that separates mechanisms, evidence, unresolved assumptions, and concrete research tasks.

Difficulty1.0

Skills

observationdata logging

Tools

  • spreadsheet
  • Cathedral notes

Datasets

  • dataset to identify

Work package

4 micro-problems

0 resolved

0% reported progress

Use this page

Start with Tier 1 if the field is unclear.

Use Tier 2 to separate claims from evidence.

Use Tier 3 and 4 when the bottleneck is testable.

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Tier 2open

Map claims and evidence for Why chain: Artemisinin Resistance

Separate claims, assumptions, measurements, and missing evidence. Link every claim to at least one source or counterexample.

Current knowledge

Why does Artemisinin Resistance work the way Cathedral currently explains it? Build a recursive why-chain that separates mechanisms, evidence, unresolved assumptions, and concrete research tasks.

Difficulty2.0

Skills

literature reviewevidence mapping

Tools

  • Semantic Scholar
  • Cathedral research table

Datasets

  • dataset to identify
Tier 3open

Model the bottleneck in Why chain: Artemisinin Resistance

Create one falsifiable model of the bottleneck. State what observation would break it.

Current knowledge

Why does Artemisinin Resistance work the way Cathedral currently explains it? Build a recursive why-chain that separates mechanisms, evidence, unresolved assumptions, and concrete research tasks.

Difficulty3.0

Skills

modelingstatistics

Tools

  • notebook
  • graph model

Datasets

  • dataset to identify
Tier 4open

Design a decisive test for Why chain: Artemisinin Resistance

Define the smallest ethical test that distinguishes the top competing explanations.

Current knowledge

Why does Artemisinin Resistance work the way Cathedral currently explains it? Build a recursive why-chain that separates mechanisms, evidence, unresolved assumptions, and concrete research tasks.

Difficulty4.0

Skills

experimental designdomain review

Tools

  • protocol template
  • review queue

Datasets

  • dataset to identify